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It should be noted that most of these clinical trials were run on mice, and no clinical trials have proven a conclusive link between clinical depression and Accutane use in humans.
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Users of Accutane may experience any of the following most common side effects: severe acne flare, skin dryness, peeling skin, flushing, nose bleeds, reduced tolerance to contact lenses, temporary, or permanent, hair loss, and even back pain.

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